Hydrazine hydrate (1:1) → 6-amino-3-thiophen-2-yl-1H-quinoxalin-2-one

HRID 548399

반응식

HRID 548399 반응식
[N+:1]([C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[C:8]([C:15]1[S:16][CH:17]=[CH:18][CH:19]=1)=[N:7]2)([O-])=O.NN.O>[Pd].CO>[NH2:1][C:4]1[CH:5]=[C:6]2[C:11](=[CH:12][CH:13]=1)[NH:10][C:9](=[O:14])[C:8]([C:15]1[S:16][CH:17]=[CH:18][CH:19]=1)=[N:7]2

참가 물질

5

반응물 2

HCID 24654Hydrazine hydrate (1:1)HCID 210836686-Nitro-3-thiophen-2-yl-1H-quinoxalin-2-one

생성물 1

HCID 210836606-amino-3-thiophen-2-yl-1H-quinoxalin-2-one

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

The quinoxalin-2-one of the present example is prepared by reducing 6-nitro-3-thiophen-2-yl-1H-quinoxalin-2-one of Example 39 with H2NNH2.H2O in the presence of Pd/C in refluxing MeOH.

출처 및 근거

ORD 기록
ord-f63bf4882daf4f3fbbb6f2cd31e35c35
출처 데이터셋
uspto-grants-2011_05
특허 번호
USRE042375E1

연결된 노트

불러오는 중…