Methyl bromoacetate → Methyl (4-nitro-1-imidazolyl)acetate

HRID 553087노트

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HRID 553087 반응식
[N+:1]([C:4]1[N:5]=[CH:6][NH:7][CH:8]=1)([O-:3])=[O:2].[CH3:9][O:10][C:11](=[O:14])[CH2:12]Br>>[CH3:9][O:10][C:11](=[O:14])[CH2:12][N:7]1[CH:8]=[C:4]([N+:1]([O-:3])=[O:2])[N:5]=[CH:6]1

참가 물질

3

반응물 2

HCID 60984Methyl bromoacetateHCID 178526856HCID 178526856, 화합물

생성물 1

HCID 3103698Methyl (4-nitro-1-imidazolyl)acetate

실험 절차

4-nitroimidazole was alkylated with bromo-acetic acid methyl ester to provide the title compound: 1H NMR (400 MHz) 3.82 (s, 1H), 4.80, (s, 2H), 7.47 (d, 1H, J=1.7 Hz), 7.84 (d, 1H, J=1.7 Hz); gc/ms m/z 185 (M).

출처 및 근거

ORD 기록
ord-41d73d42a0b144f2a5060afc44e63a06
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07951958B2

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