Sodium Hydroxide → HCID 19957436, 화합물

HRID 55314노트

반응식

HRID 55314 반응식
C[O:2][C:3](=[O:33])[CH2:4][CH2:5][C:6]1[C:11]([O:12][CH2:13][CH2:14][CH2:15][CH2:16]/[CH:17]=[CH:18]/[C:19]2[CH:24]=[CH:23][C:22]([O:25][CH3:26])=[CH:21][CH:20]=2)=[CH:10][CH:9]=[C:8]([CH2:27][CH2:28][CH2:29][CH2:30][CH2:31][OH:32])[N:7]=1.[OH-].[Na+]>CO>[OH:32][CH2:31][CH2:30][CH2:29][CH2:28][CH2:27][C:8]1[N:7]=[C:6]([CH2:5][CH2:4][C:3]([OH:33])=[O:2])[C:11]([O:12][CH2:13][CH2:14][CH2:15][CH2:16]/[CH:17]=[CH:18]/[C:19]2[CH:20]=[CH:21][C:22]([O:25][CH3:26])=[CH:23][CH:24]=2)=[CH:10][CH:9]=1

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 677037863-{6-(5-hydroxypentyl)-3-[6-(4-methoxyphenyl)-(5E)-5-hexenyloxy]-2-pyridyl}-propionic acid methyl ester

생성물 1

HCID 19957436HCID 19957436, 화합물수율 83.1%

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

Under the conditions of example 3 C, 400 mg of 3-{6-(5-hydroxypentyl)-3-[6-(4-methoxyphenyl)-(5E)-5-hexenyloxy]-2-pyridyl}-propionic acid methyl ester in 20 ml of methanol is saponified with 12 ml of 2n sodium hydroxide solution and worked up. 322 mg of the title compound is obtained as oil.

출처 및 근거

ORD 기록
ord-0dcdf700c2f24eb1827b1265bd328570
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05624943

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