N-bromobutanimide → Methyl 5-bromo-4-ethyl-1H-pyrrole-3-carboxylate

HRID 554232노트

반응식

HRID 554232 반응식
[CH2:1]([C:3]1[C:4]([C:8]([O:10][CH3:11])=[O:9])=[CH:5][NH:6][CH:7]=1)[CH3:2].[Br:12]N1C(=O)CCC1=O>>[Br:12][C:7]1[NH:6][CH:5]=[C:4]([C:8]([O:10][CH3:11])=[O:9])[C:3]=1[CH2:1][CH3:2]

참가 물질

3

반응물 2

HCID 67184N-bromobutanimideHCID 53419689Methyl 4-ethyl-1H-pyrrole-3-carboxylate

생성물 1

HCID 66924658Methyl 5-bromo-4-ethyl-1H-pyrrole-3-carboxylate수율 84.2%

실험 절차

Using methyl 4-ethyl-1H-pyrrole-3-carboxylate (2.32 g) and N-bromosuccinimide (2.74 g), a procedure as in Reference Example 40 was performed to give the title compound as white crystals (yield 2.96 g, 84%).

출처 및 근거

ORD 기록
ord-07b1d3993820449baaabf67b144811ce
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08048909B2

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