반응식
[CH3:1]I.N1C2[C:6](=[CH:7][CH:8]=CC=2)[CH:5]=[C:4]1[C:12](O)=O.[C:15](=[O:18])([O-])[O-:16].[K+].[K+].[CH3:21][N:22]([CH3:25])[CH:23]=O>>[CH3:21][N:22]1[C:25]2[C:4](=[CH:5][CH:6]=[CH:7][CH:8]=2)[CH:12]=[C:23]1[C:15]([O:16][CH3:1])=[O:18]참가 물질
5
반응 조건
- 온도
- 100 °C
실험 절차
6.0 ml of methyl iodide were added dropwise to a mixture of 5.00 g of indole-2-carboxylic acid, 100 ml of dimethylformamide and 13.0 g of anhydrous potassium carbonate, and the resulting mixture was stirred at 100° C. for 6 hours. At the end of this time, the reaction mixture was worked up following the procedure described in Preparation 5, to give 5.12 g of the title compound, melting at 91.3°-92.8° C.
후처리
- customdescribed in Preparation 5
출처 및 근거
- ORD 기록
- ord-70370978da1647d0b093740de1e756f4
- 출처 데이터셋
- uspto-grants-1997_04
- 특허 번호
- US05624935
연결된 노트
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