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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 555735생성일: 2026년 10월 26일

Bromoacetonitrile → [4-(3-Methoxy-propyl)-piperazin-1-yl]acetonitrile

https://huagongshe.com/reaction/555735

반응식

참여 물질

역할이름HCID투입량
반응물BromoacetonitrileHCID 11534—
반응물1-(3-Methoxypropyl)piperazineHCID 1822536—
생성물[4-(3-Methoxy-propyl)-piperazin-1-yl]acetonitrileHCID 63337188—

반응 단계

The title compound is synthesized by coupling of 1-(3-Methoxy-propyl)-piperazine (commercially available from CHESS GmbH) and bromoacetonitrile analogously to the preparation of Intermediate 149.2 as a colorless oil; ES-MS: M+=198.2: 1HNMR(DMSO-d6) 3.65 (s, 2H), 3.30 (s, 3H), 2.45-2.20 (m, 12H), 1.65-1.55 (m, 2H).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08053457B2
출처 데이터셋uspto-grants-2011_11
ORD IDord-5a961d53f151413babf4cc3829fa4668
출처 메모uspto-grants-2011_11