Iodoethane → HCID 59639564, 화합물

HRID 556587노트

반응식

HRID 556587 반응식
[F:1][C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][C:3]=1[C:8]1[C:9]2[CH:19]=[CH:18][C:17](=[O:20])[NH:16][C:10]=2[N:11]=[C:12]([S:14][CH3:15])[N:13]=1.I[CH2:22][CH3:23]>>[CH2:22]([N:16]1[C:10]2[N:11]=[C:12]([S:14][CH3:15])[N:13]=[C:8]([C:3]3[CH:4]=[CH:5][CH:6]=[CH:7][C:2]=3[F:1])[C:9]=2[CH:19]=[CH:18][C:17]1=[O:20])[CH3:23]

참가 물질

3

반응물 2

HCID 6340IodoethaneHCID 59639533HCID 59639533, 화합물

생성물 1

HCID 59639564HCID 59639564, 화합물

실험 절차

Prepared as described above in Example 108 starting from 4-(2-fluoro-phenyl)-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one and iodoethane to afford the title compound 8-ethyl-4-(2-fluoro-phenyl)-2-methylsulfanyl-8H-pyrido[2,3-d]pyrimidin-7-one. LC MS (m/e)=316 (MH+). Rt=2.29 min

후처리

  1. customPrepared

출처 및 근거

ORD 기록
ord-9aaf49a2416e41fa99826b8b08989426
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08058282B2

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