Vanillin → 4-((1E)-2-(((E)-4-Hydroxy-3-methoxystyrylsulfonyl)methylsulfonyl)vinyl)-2-methoxyphenol

HRID 557094노트

반응식

HRID 557094 반응식
[CH3:1][O:2][C:3]1[CH:4]=[C:5]([CH:8]=[CH:9][C:10]=1[OH:11])[CH:6]=O.C([CH2:15][S:16]([CH2:19][S:20]([CH2:23][C:24](O)=O)(=[O:22])=[O:21])(=[O:18])=[O:17])(O)=O>C(O)(=O)C>[OH:11][C:10]1[CH:9]=[CH:8][C:5](/[CH:24]=[CH:23]/[S:20]([CH2:19][S:16](/[CH:15]=[CH:6]/[C:5]2[CH:8]=[CH:9][C:10]([OH:11])=[C:3]([O:2][CH3:1])[CH:4]=2)(=[O:17])=[O:18])(=[O:21])=[O:22])=[CH:4][C:3]=1[O:2][CH3:1]

참가 물질

4

반응물 2

HCID 1183VanillinHCID 2252641Acetic acid, 2,2'-[methylenebis(sulfonyl)]bis-

생성물 1

HCID 866192214-((1E)-2-(((E)-4-Hydroxy-3-methoxystyrylsulfonyl)methylsulfonyl)vinyl)-2-methoxyphenol수율 60%

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A solution of 3-methoxy-4-hydroxybenzaldehyde (2 mmol) and carboxymethane-sulfonylmethanesulfonyl-acetic acid (1 mmol) in acetic acid (10 mL) was subjected to General Procedure 1, to yield the title compound in 60% yield. m.p. 125-127° C.

출처 및 근거

ORD 기록
ord-5127e077ce144504aba1547ba5eff533
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08058313B2

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