1,3-Dimethyl-5-nitroisoquinoline → 1,3-Dimethylisoquinolin-5-amine

HRID 559476

반응식

HRID 559476 반응식
[CH3:1][C:2]1[C:11]2[C:6](=[C:7]([N+:12]([O-])=O)[CH:8]=[CH:9][CH:10]=2)[CH:5]=[C:4]([CH3:15])[N:3]=1>[Pd].CO>[NH2:12][C:7]1[CH:8]=[CH:9][CH:10]=[C:11]2[C:6]=1[CH:5]=[C:4]([CH3:15])[N:3]=[C:2]2[CH3:1]

참가 물질

4

반응물 1

HCID 574567801,3-Dimethyl-5-nitroisoquinoline

생성물 1

HCID 223376241,3-Dimethylisoquinolin-5-amine

시약·촉매·용매 2

HCID 23938Palladium촉매HCID 887Methanol용매

실험 절차

A solution of D3 (2.01 g, 9.94 mM) and 10% palladium on charcoal (1 g) in methanol was hydrogenated at atmospheric pressure for 1 h. The catalyst was filtered off and the filtrate concentrated under reduced pressure to afford the title compound as an off white solid.

후처리

  1. filtrationThe catalyst was filtered off
  2. concentrationthe filtrate concentrated under reduced pressure

출처 및 근거

ORD 기록
ord-8b298f91f862430fb1b4d0d9f7fe359c
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063078B2

연결된 노트

불러오는 중…