Sodium Iodide → 1-Benzenesulfonyl-4-(3-bromo-phenyl)-3-isopropyl-imidazolidin-2-one

HRID 560095

반응식

HRID 560095 반응식
[C:1]1([S:7]([N:10]2[CH2:12][CH:11]2[C:13]2[CH:18]=[CH:17][CH:16]=[C:15]([Br:19])[CH:14]=2)(=[O:9])=[O:8])[CH:6]=[CH:5][CH:4]=[CH:3][CH:2]=1.[I-].[Na+].[CH:22]([N:25]=[C:26]=[O:27])([CH3:24])[CH3:23]>O1CCCC1>[C:1]1([S:7]([N:10]2[CH2:12][CH:11]([C:13]3[CH:18]=[CH:17][CH:16]=[C:15]([Br:19])[CH:14]=3)[N:25]([CH:22]([CH3:24])[CH3:23])[C:26]2=[O:27])(=[O:8])=[O:9])[CH:2]=[CH:3][CH:4]=[CH:5][CH:6]=1

참가 물질

5

반응물 3

HCID 5238Sodium IodideHCID 61277Isopropyl isocyanateHCID 866371721-Benzenesulfonyl-2-(3-bromo-phenyl)-aziridine

생성물 1

HCID 670010961-Benzenesulfonyl-4-(3-bromo-phenyl)-3-isopropyl-imidazolidin-2-one

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

In analogy to example 1, step 2,1-benzenesulfonyl-2-(3-bromo-phenyl)-aziridine (example 5, step 1) was reacted with sodium iodide and isopropyl isocyanate in tetrahydrofuran to give 1-benzenesulfonyl-4-(3-bromo-phenyl)-3-isopropyl-imidazolidin-2-one as a colorless oil.

출처 및 근거

ORD 기록
ord-5d290c62e6f5488abde95da348295adc
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08063088B2

연결된 노트

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