Thiourea → Methyl 2-amino-5-(3-(trifluoromethyl)phenyl)thiazole-4-carboxylate
반응식
[CH3:1][O:2][C:3](=[O:18])[C:4](=O)[CH:5](Cl)[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]([F:15])([F:14])[F:13])[CH:7]=1.[NH2:19][C:20]([NH2:22])=[S:21]>>[CH3:1][O:2][C:3]([C:4]1[N:19]=[C:20]([NH2:22])[S:21][C:5]=1[C:6]1[CH:11]=[CH:10][CH:9]=[C:8]([C:12]([F:15])([F:14])[F:13])[CH:7]=1)=[O:18]참가 물질
3
실험 절차
prepared by reaction of 3-chloro-3-(3-trifluoromethyl-phenyl)-2-oxo-propionic acid methyl ester with thiourea. LC-MS: tR=0.86 min; [M+H]+=303.3.
출처 및 근거
- ORD 기록
- ord-918c52b6c2354828b86bb0c9d2daf90d
- 출처 데이터셋
- uspto-grants-2011_11
- 특허 번호
- US08063099B2
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