Ethyl bromoacetate → HCID 86620464, 화합물
반응식
[Br:1][C:2]1[CH:24]=[CH:23][C:22]([F:25])=[CH:21][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11]2[N:15]=[C:14]([C:16]3[CH:17]=[N:18][NH:19][CH:20]=3)[O:13][N:12]=2)[CH2:7][CH2:6]1.[H-].[Na+].Br[CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31]>>[Br:1][C:2]1[CH:24]=[CH:23][C:22]([F:25])=[CH:21][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11]2[N:15]=[C:14]([C:16]3[CH:17]=[N:18][N:19]([CH2:29][C:30]([O:32][CH2:33][CH3:34])=[O:31])[CH:20]=3)[O:13][N:12]=2)[CH2:7][CH2:6]1참가 물질
4
실험 절차
The title compound was prepared in a similar manner as described in Example 7 (step 4) from 4-(2-bromo-5-fluorophenoxy)-1-[5-(1H-pyrazol-4-yl)-1,2,4-oxadiazol-3-yl]piperidine, sodium hydride and ethyl bromoacetate.
출처 및 근거
- ORD 기록
- ord-3453f49ac1dc4344bfce60c4a80d23ff
- 출처 데이터셋
- uspto-grants-2011_11