Sodium Hydroxide → HCID 59738184, 화합물

반응식

[Br:1][C:2]1[CH:30]=[CH:29][C:28]([F:31])=[CH:27][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11]2[N:15]=[C:14]([C:16]3[CH:17]=[N:18][N:19]([CH2:21][C:22]([O:24]CC)=[O:23])[CH:20]=3)[O:13][N:12]=2)[CH2:7][CH2:6]1.[OH-].[Na+]>>[Br:1][C:2]1[CH:30]=[CH:29][C:28]([F:31])=[CH:27][C:3]=1[O:4][CH:5]1[CH2:10][CH2:9][N:8]([C:11]2[N:15]=[C:14]([C:16]3[CH:17]=[N:18][N:19]([CH2:21][C:22]([OH:24])=[O:23])[CH:20]=3)[O:13][N:12]=2)[CH2:7][CH2:6]1

참가 물질

반응물 2

HCID 14798Sodium Hydroxide

HCID 86620464HCID 86620464, 화합물

생성물 1

HCID 59738184HCID 59738184, 화합물

실험 절차

The title compound was prepared in a similar manner as described in Example 7 (step 5) from ethyl (4-{3-[4-(2-bromo-5-fluorophenoxy)piperidin-1-yl]-1,2,4-oxadiazol-5-yl}-1H-pyrazol-1-yl)acetate and aqueous NaOH.

출처 및 근거

ORD 기록: ord-fca4263f4b8d44eb9b822f917e22d96a
출처 데이터셋: uspto-grants-2011_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US08063224B2

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