Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Triethylamine → N-(3-ethoxypropyl)-2-fluoro-4-nitroaniline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Triethylamine | HCID 8471 | — |
| 반응물 | Propanolamine ethyl ether | HCID 22720 | — |
| 반응물 | 1,2-Difluoro-4-nitrobenzene | HCID 123053 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | N-(3-ethoxypropyl)-2-fluoro-4-nitroaniline | HCID 28972577 | 90% |
반응 단계
To a solution of 3,4-difluoronitrobenzene (6.36 g, 40 mmol) in EtOAc (60 mL) were added Et3N (12.14 g, 120 mmol) and 3-ethoxypropan-1-amine (4.54 g, 44 mmol). The reaction mixture was refluxed overnight, then cooled to rt and concentrated in vacuo to give the title compound as yellow oil (8.68 g, 90%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US09434695B2 |
| 출처 데이터셋 | uspto-grants-2016_09 |
| ORD ID | ord-c1932aaead9146289c1cb1541dfbdc8b |
| 출처 메모 | uspto-grants-2016_09 |