Sulfur dichloride → 2-(Cyclohexyloxy)acetyl chloride

반응식

[CH:1]1([O:7][CH2:8][C:9]([OH:11])=O)[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1.[Cl:12]SCl>>[CH:1]1([O:7][CH2:8][C:9]([Cl:12])=[O:11])[CH2:6][CH2:5][CH2:4][CH2:3][CH2:2]1

참가 물질

반응물 2

HCID 25353Sulfur dichloride

HCID 191994Cyclohexoxyacetic acid

생성물 1

HCID 124841232-(Cyclohexyloxy)acetyl chloride

실험 절차

A mixture of 2-(cyclohexyloxy)acetic acid (0.90 g, 5.69 mmol) and dichlorosulfane (10 mL) was refluxed for 2 h. The mixture was cooled to rt and concentrated in vacuo to give the title compound as yellow oil, which was used for next step without further purification.

후처리

temperaturewas refluxed for 2 h
concentrationconcentrated in vacuo

출처 및 근거

ORD 기록: ord-8af8cc706d3a457badbaab90d0f5f777
출처 데이터셋: uspto-grants-2016_09
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09434695B2

반응 노트

불러오는 중…