Ethanol → Ethyl 3-bromo-4-methoxyphenylacetate

HRID 563594

반응식

HRID 563594 반응식
[Br:1][C:2]1[CH:3]=[C:4]([CH2:10][C:11]([OH:13])=[O:12])[CH:5]=[CH:6][C:7]=1[O:8][CH3:9].[CH3:14][CH2:15]O>S(=O)(=O)(O)O>[CH2:14]([O:12][C:11](=[O:13])[CH2:10][C:4]1[CH:5]=[CH:6][C:7]([O:8][CH3:9])=[C:2]([Br:1])[CH:3]=1)[CH3:15]

참가 물질

4

반응물 2

HCID 702EthanolHCID 1366153-Bromo-4-methoxyphenylacetic acid

생성물 1

HCID 57419861Ethyl 3-bromo-4-methoxyphenylacetate

시약·촉매·용매 1

HCID 1118Sulfuric Acid용매

실험 절차

A solution of 3-bromo-4-methoxyphenylacetic acid (3.0 g, 12.2 mmol) in EtOH and sulfuric acid was stirred at 100° C. for 2 hours. The mixture was concentrated and partitioned between EtOAc and H2O, and the organic layer was separated to give the title compound.

후처리

  1. concentrationThe mixture was concentrated
  2. custompartitioned between EtOAc and H2O
  3. customthe organic layer was separated

출처 및 근거

ORD 기록
ord-e3d6e9063a61482c9b1a0e69f21c57b7
출처 데이터셋
uspto-grants-2011_11
특허 번호
US08067445B2

연결된 노트

불러오는 중…