Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2,6-Difluoro-3-nitrobenzoic acid → 3-Amino-2,6-difluorobenzoic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2,6-Difluoro-3-nitrobenzoic acid | HCID 302629 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | HCID 178418390 | HCID 178418390 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 3-Amino-2,6-difluorobenzoic acid | HCID 18405352 | 93% |
반응 단계
A solution of 2,6-difluoro-3-nitrobenzoic acid and 10% palladium carbon added to 10 ml of methanol was stirred in a hydrogen atmosphere at room temperature for 2 hours. The catalyst was filtered off and then the solvent was removed under a reduced pressure to obtain the desired product (Yield: 93%) as a white solid.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08067638B2 |
| 출처 데이터셋 | uspto-grants-2011_11 |
| ORD ID | ord-3341bca4d0554b49aae95f7eac297a40 |
| 출처 메모 | uspto-grants-2011_11 |