3-Chloropyridin-4-amine → HCID 86756187, 화합물

HRID 564731

반응식

HRID 564731 반응식
[N+](C1C=CC(O[C:11]([C:13]2[C:14]3[CH:23]=[C:22]([CH2:24][CH3:25])[O:21][C:15]=3[C:16]([O:19][CH3:20])=[N:17][CH:18]=2)=[O:12])=CC=1)([O-])=O.[NH2:26][C:27]1[CH:32]=[CH:31][N:30]=[CH:29][C:28]=1[Cl:33]>>[Cl:33][C:28]1[CH:29]=[N:30][CH:31]=[CH:32][C:27]=1[NH:26][C:11]([C:13]1[C:14]2[CH:23]=[C:22]([CH2:24][CH3:25])[O:21][C:15]=2[C:16]([O:19][CH3:20])=[N:17][CH:18]=1)=[O:12]

참가 물질

3

반응물 2

HCID 5818533-Chloropyridin-4-amineHCID 541193452-Ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester

생성물 1

HCID 86756187HCID 86756187, 화합물수율 72.2%

실험 절차

Starting from 2-ethyl-7-methoxyfuro[2,3-c]pyridine-4-carboxylic acid 4-nitrophenyl ester (0.20 g) and 4-amino-3-chloropyridine (0.15 g). Purification by column chromatography on silica eluting with 50% hexane in ethyl acetate gave the title compound (0.14 g) as a white solid.

후처리

  1. customPurification by column chromatography on silica eluting with 50% hexane in ethyl acetate

출처 및 근거

ORD 기록
ord-8717e5760ffe49bc8e92bec4d4f5d370
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06169090A

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