Lauryldimethylamine → HCID 22111399, 화합물

HRID 565586

반응식

HRID 565586 반응식
[CH3:1][N:2]([CH3:15])[CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14].[Cl:16][CH2:17][S:18][C:19]#[N:20]>O1CCCC1>[Cl-:16].[CH3:1][N+:2]([CH3:15])([CH2:3][CH2:4][CH2:5][CH2:6][CH2:7][CH2:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH3:14])[CH2:17][S:18][C:19]#[N:20]

참가 물질

4

반응물 2

HCID 8168LauryldimethylamineHCID 76755Thiocyanic acid, chloromethyl ester

생성물 1

HCID 22111399HCID 22111399, 화합물수율 79.4%

시약·촉매·용매 1

HCID 8028Tetrahydrofuran용매

실험 절차

A 2 liter flask was charged with 1 liter of tetrahydrofuran, 277 g of dimethyldodecylamine and then 153.7 g of chloromethylthiocyanate. The reaction mixture was stirred at ambient temperature for 17 hours. A considerable amount of solids was formed. The reaction was then stirred for 7 more hours at 35° C. The solid was filtered off with suction and the solid washed with diethyl ether. The filtrate now formed more solid which was filtered off, washed with ether and then combined with the other solid. The combined solids were now allowed to air dry to constant weight, 331.0 g, for a 79.4% yield. Analysis (nmr) showed a purity of better than 98%.

후처리

  1. customA considerable amount of solids was formed
  2. stirringThe reaction was then stirred for 7 more hours at 35° C
  3. filtrationThe solid was filtered off with suction
  4. washthe solid washed with diethyl ether
  5. customThe filtrate now formed more solid which
  6. filtrationwas filtered off
  7. washwashed with ether
  8. customto air dry to constant weight, 331.0 g, for a 79.4% yield

출처 및 근거

ORD 기록
ord-eb7a11205d7645a18d93c723d47218df
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06172117B2

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