Diethyl benzylphosphonate → Benzylphosphonic Acid

HRID 565992

반응식

HRID 565992 반응식
[CH2:1]([P:8](=[O:15])([O:12]CC)[O:9]CC)[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1>CO.Cl>[CH2:1]([P:8](=[O:9])([OH:15])[OH:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

4

반응물 1

HCID 14122Diethyl benzylphosphonate

생성물 1

HCID 81312Benzylphosphonic Acid수율 59.2%

시약·촉매·용매 2

HCID 313Hydrochloric Acid용매HCID 887Methanol용매

실험 절차

A solution of diethyl benzylphosphonate (25 g) in methanol (10 ml) and concentrated hydrochloric acid (500 ml) solution was refluxed for 4 days. The mixture was cooled to room temperature, and precipitated crystal was collected by filtration to give benzylphosphonic acid (11.17 g) as colorless crystals.

후처리

  1. customprecipitated crystal
  2. filtrationwas collected by filtration

출처 및 근거

ORD 기록
ord-dde78dcacfcc4ea3b3cf341bf25c2323
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06172061B2

연결된 노트

불러오는 중…