2,6-Difluorobenzoyl chloride → HCID 21262479, 화합물

HRID 567677

반응식

HRID 567677 반응식
[NH2:1][C:2]1[CH:10]=[CH:9][CH:8]=[C:7]([CH3:11])[C:3]=1[C:4]([OH:6])=[O:5].[F:12][C:13]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:14]=1[C:15](Cl)=O.C(NC1C=CC2N=C(C3C(F)=CC=CC=3F)OC(=O)C=2C=1)(=O)C>C(N(CC)CC)C.C1(C)C=CC=CC=1>[F:12][C:13]1[CH:21]=[CH:20][CH:19]=[C:18]([F:22])[C:14]=1[C:15]1[O:5][C:4](=[O:6])[C:3]2[C:7]([CH3:11])=[CH:8][CH:9]=[CH:10][C:2]=2[N:1]=1

참가 물질

5

반응물 3

HCID 874382,6-Difluorobenzoyl chlorideHCID 1512106-Methylanthranilic acidHCID 99488136-Acetamido-(2,6-difluoro-phenyl)-benzo[d][1,3]oxazin-4-one

생성물 1

HCID 21262479HCID 21262479, 화합물

시약·촉매·용매 1

HCID 22504574Toluene triethylamine용매

실험 절차

2-Amino-6-methylbenzoic acid (0.498 g), 2,6-difluorobenzoyl chloride (0.93 mL) and triethyl amine/toluene (1/1) (20 mL) were reacted as described under (10).

출처 및 근거

ORD 기록
ord-3b042ae8eaad4006bc28228c70a460e6
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06180625B2

연결된 노트

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