Hydrochloric Acid → 3-Nitryloxy-2,2-bis(nitryloxymethyl)propionic acid hydrazide

HRID 567932노트

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HRID 567932 반응식
[N+:1]([O:4][CH2:5][C:6]([CH2:16][O:17][N+:18]([O-:20])=[O:19])([CH2:11][O:12][N+:13]([O-:15])=[O:14])[C:7](OC)=[O:8])([O-:3])=[O:2].Cl.[NH2:22][NH2:23].Cl>>[N+:1]([O:4][CH2:5][C:6]([CH2:16][O:17][N+:18]([O-:20])=[O:19])([CH2:11][O:12][N+:13]([O-:15])=[O:14])[C:7]([NH:22][NH2:23])=[O:8])([O-:3])=[O:2]

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 115031Hydrazinium chlorideHCID 15380869Methyl 2,2-bis(nitryloxymethyl)-3-nitryloxypropionate

생성물 1

HCID 153808743-Nitryloxy-2,2-bis(nitryloxymethyl)propionic acid hydrazide수율 63%

실험 절차

1 g (3.5 mmol) of methyl 2,2-bis(nitryloxymethyl)-3-nitryloxypropionate is heated for 5 hours in a water bath with excess aqueous hydrazine hydrochloride solution. The mixture is poured onto ice and weakly acidified with hydrochloric acid. The oil which has deposited is separated by column chromatography to give 3-nitryloxy-2,2-bis(nitryloxymethyl)propionic acid hydrazide (Tri-PA hydrazide) as a colourless oil. Yield: 63%. Elemental analysis: (C: conforms, H: conforms, N: conforms).

후처리

  1. additionThe mixture is poured onto ice
  2. customThe oil which has deposited is separated by column chromatography

출처 및 근거

ORD 기록
ord-907267379249417fb39aad15005fd53e
출처 데이터셋
uspto-grants-2001_01
특허 번호
US06180664B2

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