Sodium Dithionite → 1,3-Di-cyclopropyl-8-amino Xanthine
반응식
[CH:1]1([N:4]2[C:13](=[O:14])[C:12]3[NH:11][C:10]([N+:15]([O-])=O)=[N:9][C:8]=3[N:7]([CH:18]3[CH2:20][CH2:19]3)[C:5]2=[O:6])[CH2:3][CH2:2]1.S(S([O-])=O)([O-])=O.[Na+].[Na+]>CO.O>[CH:1]1([N:4]2[C:13](=[O:14])[C:12]3[NH:11][C:10]([NH2:15])=[N:9][C:8]=3[N:7]([CH:18]3[CH2:20][CH2:19]3)[C:5]2=[O:6])[CH2:3][CH2:2]1참가 물질
5
실험 절차
1,3-Di-cyclopropyl-8-nitro xanthine (0.4 g, 0.0014 mol) was dissolved in methanol (20 ml) and treated with a sodium dithionite solution in water (0.5 g in 5 ml) at room temperature with stirring. After stirring for three hours the solvent was removed in vacuo, the residue taken up with dichloromethane and extracted with water (40 ml).
후처리
- stirringAfter stirring for three hours the solvent
- customwas removed in vacuo
- extractionextracted with water (40 ml)
출처 및 근거
- ORD 기록
- ord-8fc34d0938c940a3a98edba659c5d90d
- 출처 데이터셋
- uspto-grants-2001_01
- 특허 번호
- US06180791B2
반응 노트
불러오는 중…