Water → 6-Chloro-3-hydrazinylpyridazin-4-amine

HRID 568304노트

반응식

HRID 568304 반응식
[NH2:1][C:2]1[CH:7]=[C:6]([Cl:8])[N:5]=[N:4][C:3]=1Cl.O.[NH2:11][NH2:12].O>C(O)C>[NH:11]([C:3]1[N:4]=[N:5][C:6]([Cl:8])=[CH:7][C:2]=1[NH2:1])[NH2:12]

참가 물질

5

반응물 3

HCID 962WaterHCID 24654Hydrazine hydrate (1:1)HCID 2984983,6-Dichloropyridazin-4-amine

생성물 1

HCID 2500056-Chloro-3-hydrazinylpyridazin-4-amine

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A stirred solution of 2.0 grams of 4-amino-3,6-dichloropyridazine and 2.5 ml of hydrazine hydrate in 20 ml of ethanol is heated under reflux for three hours. After this time water is added to the reaction mixture and the resultant precipitate collected by filtration. The filter cake is recrystallized from ethanol to yield 2.3 grams of 3-hydrazino-4-amino-6-chloropyridazine; m.p. 190° C.

후처리

  1. temperatureunder reflux for three hours
  2. filtrationthe resultant precipitate collected by filtration
  3. customThe filter cake is recrystallized from ethanol

출처 및 근거

ORD 기록
ord-9262f59e53564d418d7ceaa4d65c56e9
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04728355

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