Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
N-methylcyclopentanamine → N-(4-pyridazinyl)-N'-cyclopentyl-N'-methylurea
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | N-methylcyclopentanamine | HCID 7020624 | — |
| 반응물 | Phenyl pyridazin-4-ylcarbamate | HCID 14099147 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | N-(4-pyridazinyl)-N'-cyclopentyl-N'-methylurea | HCID 20150035 | — |
반응 단계
A stirred solution of 2.0 grams of phenyl N-(4-pyridazinyl)carbamate (prepared as in Example 2, Step A) and 0.9 gram of N-cyclopentyl-N-methyl amine in tetrahydrofuran is heated under reflux for 18 hours. The reaction mixture is filtered and the filtrate concentrated under reduced pressure to a residue. The residue is purified by column chromatography on silica gel to yield N-(4-pyridazinyl)-N'-cyclopentyl-N'-methylurea.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04728355 |
| 출처 데이터셋 | uspto-grants-1988_03 |
| ORD ID | ord-4f364a08bbb1497aba4f90badbd625b0 |
| 출처 메모 | uspto-grants-1988_03 |