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Butyl bromide → HCID 54483300, 화합물

HRID 569617
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HRID 569617 반응식
[CH2:1]([O:5][CH:6]([P:15](=[O:22])([O:19][CH2:20][CH3:21])[O:16][CH2:17][CH3:18])[P:7](=[O:14])([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10])[CH2:2][CH2:3][CH3:4].CC(C)([O-])C.[K+].[CH2:29](Br)[CH2:30][CH2:31][CH3:32]>C(O)(C)(C)C.C(OCC)(=O)C>[CH2:1]([O:5][C:6]([P:15](=[O:22])([O:19][CH2:20][CH3:21])[O:16][CH2:17][CH3:18])([P:7](=[O:14])([O:11][CH2:12][CH3:13])[O:8][CH2:9][CH3:10])[CH2:29][CH2:30][CH2:31][CH3:32])[CH2:2][CH2:3][CH3:4]
참가 물질실험 절차후처리출처 및 근거반응 노트

참가 물질

6

반응물 3

HCID 8002Butyl bromideHCID 13613503HCID 13613503, 화합물HCID 23665647Potassium tert-butoxide

생성물 1

HCID 54483300HCID 54483300, 화합물

시약·촉매·용매 2

HCID 6386tert-Butanol용매HCID 8857Ethyl Acetate용매

실험 절차

Tetraethyl (n-butoxymethylene)-bisphosphonate (1.2 g) was added to a stirred solution of potassium tert-butoxide (0.37 g) in tert-butanol (5 ml). After 30 minutes at room temperature, butyl bromide (0.36 ml) was added, and the mixture was refluxed for 8 hours. After cooling, the mixture was diluted with ethyl acetate and washed with water. The organic phase was dried and evaporated to give an oil which was purified by chromatography to yield the title compound.

후처리

  1. temperaturethe mixture was refluxed for 8 hours
  2. temperatureAfter cooling
  3. washwashed with water
  4. customThe organic phase was dried
  5. customevaporated
  6. customto give an oil which
  7. customwas purified by chromatography

출처 및 근거

ORD 기록
ord-cecfbe3de01344198236c3836ceac600
출처 데이터셋
uspto-grants-1988_03
DOI
10.6084/m9.figshare.5104873.v1
특허 번호
US04732998

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