Methanol → Methyl 2-(carbamoylamino)ethanimidate

HRID 570035

반응식

HRID 570035 반응식
[C:1]([CH2:3][NH:4][C:5]([NH2:7])=[O:6])#[N:2].[OH-:8].[Na+].[CH3:10]O>>[CH3:10][O:8][C:1](=[NH:2])[CH2:3][NH:4][C:5]([NH2:7])=[O:6]

참가 물질

4

반응물 3

HCID 887MethanolHCID 14798Sodium HydroxideHCID 80065(Cyanomethyl)urea

생성물 1

HCID 13318648Methyl 2-(carbamoylamino)ethanimidate수율 70%

반응 조건

온도
30 °C

실험 절차

100 g of cyanomethylurea is combined with a mixture of 300 ml of methanol and 5 ml of 8N sodium hydroxide solution and stirred for 3 hours at 25°30° C. The mixture is allowed to cool to 20° C., the resultant product is removed by filtration, washed with a small amount of ice-cold methanol, and dried under vacuum, thus obtaining 92.6 g of (2-methoxy-2-iminoethyl)urea (=70% of theory).

후처리

  1. temperatureto cool to 20° C.
  2. customthe resultant product is removed by filtration
  3. washwashed with a small amount of ice-cold methanol
  4. customdried under vacuum

출처 및 근거

ORD 기록
ord-43abd032380c466b85186412985afc56
출처 데이터셋
uspto-grants-1988_03
특허 번호
US04734506

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