Methyl iodide → Methyl 4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbimidothioate hydroiodide

HRID 570941노트

반응식

HRID 570941 반응식
[O:1]=[C:2]1[N:7]([CH2:8][C:9]#[CH:10])[N:6]=[N:5][C:4]2=[C:11]([C:14](=[S:16])[NH2:15])[N:12]=[CH:13][N:3]12.[I:17][CH3:18]>CC#N>[IH:17].[CH3:18][S:16][C:14]([C:11]1[N:12]=[CH:13][N:3]2[C:2](=[O:1])[N:7]([CH2:8][C:9]#[CH:10])[N:6]=[N:5][C:4]=12)=[NH:15]

참가 물질

4

반응물 2

HCID 6328Methyl iodideHCID 498691414-Oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbothioamide

생성물 1

HCID 86663789Methyl 4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbimidothioate hydroiodide

시약·촉매·용매 1

HCID 6342Acetonitrile용매

실험 절차

4-oxo-3-(prop-2-ynyl)-3,4-dihydroimidazo[5,1-d][1,2,3,5]tetrazine-8-carbothioamide (0.323 g; 0.86 mmol) was dissolved in dry MeCN (1 mL) and iodomethane (1.220 g; 8.6 mmol) was added and the reaction mixture stirred at room temperature overnight.

출처 및 근거

ORD 기록
ord-c9eedfe3fe944eee8221b6d9f5b6b56a
출처 데이터셋
uspto-grants-2015_05
특허 번호
US09024018B2

반응 노트

불러오는 중…