Acetic Anhydride → HCID 16640801, 화합물

반응식

[CH:1]1[CH:6]=[C:5]([S:7]([OH:10])(=[O:9])=[O:8])[CH:4]=[C:3]([NH2:11])[CH:2]=1.[C:12]([O-])(=[O:14])[CH3:13].[Na+:16].C(OC(=O)C)(=O)C>>[Na+:16].[C:12]([NH:11][C:3]1[CH:4]=[C:5]([S:7]([O-:10])(=[O:8])=[O:9])[CH:6]=[CH:1][CH:2]=1)(=[O:14])[CH3:13]

참가 물질

반응물 3

HCID 7918Acetic Anhydride

HCID 84743-Aminobenzenesulfonic acid

HCID 517045Sodium Acetate

생성물 1

HCID 16640801HCID 16640801, 화합물수율 95%

실험 절차

Metanilic acid (3-aminobenzenesulfonic acid) in an amount of 37.5 parts, and 18.7 parts of sodium acetate are charged into the kneader and the procedure described and 32 parts of acetic anhydride are added to the reaction mixture. The powdery reaction mass is mixed for one hour and then dried at 85° C. in a stream of air to give a 95% yield of 3-acetylaminobenzenesulfonic acid sodium salt. Liquid chromatography and titration analysis indicated a purity of greater than 97% and the presence of about 0.5% metanilic acid.