4-Nitrobenzaldehyde → p-Nitrobenzaldoxime

HRID 580092

반응식

HRID 580092 반응식
[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=O)=[CH:6][CH:5]=1)([O-:3])=[O:2].Cl.[NH2:13][OH:14]>CO.O>[N+:1]([C:4]1[CH:11]=[CH:10][C:7]([CH:8]=[N:13][OH:14])=[CH:6][CH:5]=1)([O-:3])=[O:2]

참가 물질

5

반응물 2

HCID 5414-NitrobenzaldehydeHCID 443297Hydroxyamine hydrochloride

생성물 1

HCID 96339p-Nitrobenzaldoxime수율 94.7%

시약·촉매·용매 2

HCID 887Methanol용매HCID 962Water용매2회

반응 조건

온도
30 °C

실험 절차

52.9 g (0.35 mol) of p-nitrobenzaldehyde was dissolved in 100 ml of methanol and a solution of 27.8 g (0.38 mol) of hydroxylamine hydrochloride in 35 ml of water was added dropwise over 30 minutes while maintaining the temperature at 30° C. and then, stirred at the same temperature for two hours followed by dilution with 300 ml of water. White crystals deposited were filtered and dried to obtain 55 g of p-nitrobenzaldoxime. Yield 94.7%; M.P. 128°-131° C.

후처리

  1. filtrationWhite crystals deposited were filtered
  2. customdried

출처 및 근거

ORD 기록
ord-0f70ebd744a94e19873dae59cefcd4f0
출처 데이터셋
uspto-grants-1988_06
특허 번호
US04751328

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