Hydrochloric Acid → 3-(3-Diethylaminopropylamino)-5-aminoindazole dihydrochloride

HRID 580133노트

반응식

HRID 580133 반응식
[CH2:1]([N:3]([CH2:18][CH3:19])[CH2:4][CH2:5][CH2:6][NH:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([NH2:17])[CH:15]=2)[NH:10][N:9]=1)[CH3:2].[ClH:20].C(OCC)C>C(O)C>[ClH:20].[ClH:20].[CH2:18]([N:3]([CH2:1][CH3:2])[CH2:4][CH2:5][CH2:6][NH:7][C:8]1[C:16]2[C:11](=[CH:12][CH:13]=[C:14]([NH2:17])[CH:15]=2)[NH:10][N:9]=1)[CH3:19]

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 3283Diethyl EtherHCID 201357883-(3-Diethylaminopropylamino)-5-aminoindazole

생성물 1

HCID 201357873-(3-Diethylaminopropylamino)-5-aminoindazole dihydrochloride

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

In 15 ml of absolute ethyl alcohol was dissolved 0.6 g of 3-(3-diethylaminopropylamino)-5-aminoindazole, and into the solution was introduced dried hydrogen chloride gas under cooling with ice. To the solution was added anhydrous diethyl ether to separate crystals. Then the crystals were obtained by filtration and dried to give 3-(3-diethylaminopropylamino)-5-aminoindazole dihydrochloride having the following analytical value.

후처리

  1. temperatureunder cooling with ice
  2. customto separate crystals
  3. customThen the crystals were obtained by filtration
  4. customdried

출처 및 근거

ORD 기록
ord-902ca7c6c17e40c084c74154228125c2
출처 데이터셋
uspto-grants-1988_06
특허 번호
US04751302

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