Chlorate ion → Quinolinic Acid

HRID 580656

반응식

HRID 580656 반응식
Cl([O-])(=O)=O.[N:5]1[C:14]2[C:9](=CC=CC=2)[CH:8]=[CH:7][C:6]=1[C:15]([O-:17])=[O:16].[Cu+2:18].N1C2C(=CC=CC=2)C=CC=1[C:29]([O-:31])=[O:30]>>[Cu:18].[N:5]1[CH:14]=[CH:9][CH:8]=[C:7]([C:29]([OH:31])=[O:30])[C:6]=1[C:15]([OH:17])=[O:16]

참가 물질

4

반응물 2

HCID 104770Chlorate ion2회HCID 12554537HCID 12554537, 화합물

생성물 2

HCID 1066Quinolinic AcidHCID 23978Copper

실험 절차

In another example of a preferred embodiment of the process, a sodium chlorate solution is added in small increments to a mixture of the other components, including copper oxide, which has been previously mixed and heated to reaction temperature (99°-101° C.). The acid concentration in the mixture is about 5 equivalents of acid per liter. The total chlorate addition will provide a chlorate molar excess of about 18% relative to the quinoline present. An exotherm becomes apparent after 6-8% of the chlorate has been added, and soon thereafter a suspension of copper quinolinate develops. Total chlorate addition is completed in 2-4 hours with total reaction time of 10-12 hours. The product, crude copper salt of pyridine-2,3-dicarboxylic acid, is isolated by filtration.

후처리

  1. additionhas been added

출처 및 근거

ORD 기록
ord-10b831cc0c824b73a9aed1ac13ae8428
출처 데이터셋
uspto-grants-1988_06
특허 번호
US04754039

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