Chloral → Trichlorfon

HRID 581641

반응식

HRID 581641 반응식
[O:1]=[CH:2][C:3]([Cl:6])([Cl:5])[Cl:4].[P:7]([O-:12])([O:10][CH3:11])[O:8][CH3:9]>C1C=CC=CC=1>[CH3:9][O:8][P:7]([CH:2]([OH:1])[C:3]([Cl:6])([Cl:5])[Cl:4])(=[O:12])[O:10][CH3:11]

참가 물질

4

반응물 2

HCID 6407ChloralHCID 21884954Dimethylphosphite

생성물 1

HCID 5853Trichlorfon

시약·촉매·용매 1

HCID 241Benzene용매

실험 절차

In another process, Pesticide Manufacturing and Toxic Materials Control Encyclopedia, edited by Marshall Sittig, Noyes Data Corporation, Park Ridge, N.J. 1980, 75 grams of chloral are dropped into 60 grams of dimethyl phosphite at an initial temperature of 25° C. The temperature slowly rises to 50° C. and is kept at 50° C. to 60° C. by external cooling. After cooling the oil is dissolved in benzene, and the benzene solution is washed with a sodium bicarbonate solution and dried with anhydrous sodium sulfate. After the solvent has been distilled off, an oil is left which is almost completely solidified. After washing with an icy mixture of ether and petroleum ether, the trichloro-α-hydroxyethyl phosphonic dimethyl ester is obtained in the form of colorless needles with a melting point of about 81° C.

후처리

  1. customslowly rises to 50° C.
  2. customis kept at 50° C. to 60° C. by external cooling
  3. temperatureAfter cooling the oil
  4. washthe benzene solution is washed with a sodium bicarbonate solution
  5. dry with materialdried with anhydrous sodium sulfate
  6. distillationAfter the solvent has been distilled off
  7. waitan oil is left which
  8. washAfter washing with an icy mixture of ether and petroleum ether

출처 및 근거

ORD 기록
ord-c5ce51ce16d54ec393237a5cf910ef17
출처 데이터셋
uspto-grants-1999_07
특허 번호
US05922404

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