참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | 2,2-Dibromopropane | HCID 11658 | — |
| 반응물 | HCID 12116531 | HCID 12116531 | — |
| 용매 | HCID 86593149 | HCID 86593149 | — |
| 생성물 | HCID 178526667 | HCID 178526667 | 189.3% |
반응 단계
3.5 g (0.0135 mol) of 1-[1-(4-nitrophenyl)pyrrolidin-3-yl]-1H-imidazole were heated to 100° C. in 12 ml of a pentanol/DMF mixture (50/50). 1 g (0.005 mol) of dibromopropane was added. The reaction medium was heated at 115° C. for 17 hours. The precipitate was filtered off while hot and washed with pentanol and then with ether. After draining by suction and drying the precipitate, 3.4 g of yellow powder (4) were obtained. 33% yield.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US06923835B2 |
|---|
| 출처 데이터셋 | uspto-grants-2005_08 |
|---|
| ORD ID | ord-387f92f2044842899763467dfed4b438 |
|---|
| 출처 메모 | uspto-grants-2005_08 |
|---|
