O-Toluidine → 1-(2-Methylphenyl)-2-oxo-3-pyrrolidinecarboxylic acid
반응식
CC1(C)[O:9][C:8](=[O:10])[C:5]2([CH2:7][CH2:6]2)[C:4](=[O:11])O1.[NH2:13][C:14]1[C:15]([CH3:20])=[CH:16][CH:17]=[CH:18][CH:19]=1>C(O)C>[O:11]=[C:4]1[CH:5]([C:8]([OH:9])=[O:10])[CH2:7][CH2:6][N:13]1[C:14]1[CH:19]=[CH:18][CH:17]=[CH:16][C:15]=1[CH3:20]참가 물질
4
실험 절차
This compound was prepared according to general method 1 starting from 6,6-dimethyl-5,7-dioxaspiro[2.5]octane-4,8-dione (0.250 g, 1.47 mmol) and o-toluidine (0.470 mL; 4.41 mmol) in ethanol (3 mL). 2-oxo-1-o-tolylpyrrolidine-3-carboxylic acid 0.292 g (91%) was obtained as a white film.
후처리
- customThis compound was prepared
출처 및 근거
- ORD 기록
- ord-53d1152f05f74e8bad11f9b10c4d6e93
- 출처 데이터셋
- uspto-grants-2016_09
- 특허 번호
- US09434722B2
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