Methyl iodide → HCID 69740307, 화합물

HRID 586651노트

반응식

HRID 586651 반응식
[CH3:1][O:2][CH2:3][CH:4]1[C@H:6]([CH2:7][OH:8])[C:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1.[Si](OCC1[C@@H](CO)C1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1)(C(C)(C)C)(C)C.CI>>[CH3:1][O:2][CH2:3][CH:4]1[C@@H:6]([CH2:7][OH:8])[C:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1

참가 물질

4

반응물 3

HCID 6328Methyl iodideHCID 69738373HCID 69738373, 화합물HCID 131725079HCID 131725079, 화합물

생성물 1

HCID 69740307HCID 69740307, 화합물수율 40%

실험 절차

Following a procedure similar to that for the preparation of Intermediate 6a using Intermediate 5 as the starting material and methyl iodide as the alkylating reagent provided the title compound as a colorless oil (67 mg, 40% yield):

출처 및 근거

ORD 기록
ord-5952ac0828294bbebeb498bb4ecdc2b7
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06936636B2

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