Iodoethane → HCID 69738490, 화합물

HRID 586652노트

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HRID 586652 반응식
[CH3:1][O:2][CH2:3][CH:4]1[C@H:6]([CH2:7][OH:8])[C:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1.[Si](OCC1[C@@H](CO)C1(C)C1C=CC2C(C)(C)CCC(C)(C)C=2C=1)(C(C)(C)C)(C)[CH3:25].C(I)C>>[CH2:1]([O:2][CH2:3][CH:4]1[C@@H:6]([CH2:7][OH:8])[C:5]1([CH3:23])[C:9]1[CH:18]=[CH:17][C:16]2[C:15]([CH3:20])([CH3:19])[CH2:14][CH2:13][C:12]([CH3:22])([CH3:21])[C:11]=2[CH:10]=1)[CH3:25]

참가 물질

4

반응물 3

HCID 6340IodoethaneHCID 69738373HCID 69738373, 화합물HCID 131725079HCID 131725079, 화합물

생성물 1

HCID 69738490HCID 69738490, 화합물수율 81%

실험 절차

Following a procedure similar to that for the preparation of Intermediate 6a using Intermediate 5 as the starting material and ethyl iodide as the alkylating reagent provided the title compound (65 mg, 81% yield) as a colorless oil:

출처 및 근거

ORD 기록
ord-921ffc8b63714c6680fb4a5eb3712295
출처 데이터셋
uspto-grants-2005_08
특허 번호
US06936636B2

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