Ethanol → Salicylideneaniline
반응식
[CH:1](=O)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4].[NH2:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1.C(O)C>Cl.O>[CH:1](=[N:10][C:11]1[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=1)[C:2]1[C:3](=[CH:5][CH:6]=[CH:7][CH:8]=1)[OH:4]참가 물질
6
실험 절차
To a mixture of salicylaldehyde (40 mL, 45.84 g, 375.37 mmol)) and aniline (22 mL, 31.72 g, 374.66 mmol), was added ethanol (90 mL), 8 drops of concentrated hydrochloric acid and water (10 mL). This reaction mixture was refluxed for one hour, allowed to cool to room temperature and left in the refrigerator over the weekend. A large quantity of orange solid was formed after 2 hours in the refrigerator. It was filtered off and washed with ethanol. Recrystallisation from ethanol afforded 31.53 g of product.
후처리
- temperatureThis reaction mixture was refluxed for one hour
- waitleft in the refrigerator over the weekend
- customA large quantity of orange solid was formed after 2 hours in the refrigerator
- filtrationIt was filtered off
- washwashed with ethanol
- customRecrystallisation from ethanol
출처 및 근거
- ORD 기록
- ord-41a44524be644c5bbf2fb2ced05283ad
- 출처 데이터셋
- uspto-grants-2016_09
- 특허 번호
- US09437828B2
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