Styrene → P-Methoxystilbene

반응식

I[C:2]1[CH:7]=[CH:6][C:5]([O:8][CH3:9])=[CH:4][CH:3]=1.[CH2:10]=[CH:11][C:12]1[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=1.C(N(CC)CC)C>>[CH3:9][O:8][C:5]1[CH:6]=[CH:7][C:2](/[CH:10]=[CH:11]/[C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[CH:3][CH:4]=1

참가 물질

반응물 3

HCID 7501Styrene

HCID 8471Triethylamine

HCID 696764-Iodoanisole

생성물 1

HCID 1245920P-Methoxystilbene

실험 절차

4-Iodoanisole (58 mg, 0.25 mmol) and styrene (43 μL, 0.375 mmol) were coupled using the procedure described above, but using triethylamine (0.375 mmol, 52 μL) in place of ethyldiisopropylamine, to give 100% conversion to (E)-4-methoxystilbene by GC analysis.

출처 및 근거

ORD 기록: ord-7ae5b94b9af240a9831caff3bee98b17
출처 데이터셋: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09233366B2

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