Trimethyl orthoformate → HCID 66690797, 화합물

HRID 592294노트

반응식

[CH:1](OC)(OC)OC.[Cl:8][C:9]1[C:10]([NH:22][NH2:23])=[N:11][CH:12]=[C:13]([CH:21]=1)[C:14]([O:16][C:17]([CH3:20])([CH3:19])[CH3:18])=[O:15]>>[Cl:8][C:9]1[C:10]2[N:11]([CH:1]=[N:23][N:22]=2)[CH:12]=[C:13]([C:14]([O:16][C:17]([CH3:19])([CH3:20])[CH3:18])=[O:15])[CH:21]=1

참가 물질

반응물 2

HCID 9005Trimethyl orthoformate

HCID 66690636HCID 66690636, 화합물

생성물 1

HCID 66690797HCID 66690797, 화합물

반응 조건

온도: 85 °C

실험 절차

Trimethyl orthoformate (19 mL, 172 mmol) was added neat to tert-butyl 5-chloro-6-hydrazinonicotinate (1.9 g, 7.8 mmol). The mixture was heated to 85° C. After 4 h, the mixture was cooled to ambient temperature and concentrated to dryness: LC-MS [M+1]=254.1.

후처리

temperaturethe mixture was cooled to ambient temperature
concentrationconcentrated to dryness

출처 및 근거

ORD 기록: ord-860a9222978149548ad989cd76d51d3f
출처 데이터셋: uspto-grants-2016_01
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US09238647B2

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