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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 594562생성일: 2026년 10월 26일

1-Phenyl-1H-pyrazole-4-carbaldehyde → 5-(2,6-dimethoxyphenyl)-3-methyl-1-((1-phenyl-1H-pyrazol-4-yl)methyl)pyrrolidin-2-one

https://huagongshe.com/reaction/594562

반응식

참여 물질

역할이름HCID투입량
반응물1-Phenyl-1H-pyrazole-4-carbaldehydeHCID 952089—
반응물Ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoateHCID 69085588—
생성물5-(2,6-dimethoxyphenyl)-3-methyl-1-((1-phenyl-1H-pyrazol-4-yl)methyl)pyrrolidin-2-oneHCID 86695646—

반응 단계

Prepared according to the described general procedure 2 (GP2) by reaction of ethyl 4-amino-4-(2,6-dimethoxyphenyl)-2-methylbutanoate with commercially available 1-phenyl-1H-pyrazole-4-carbaldehyde. Subsequent purification by preparative HPLC afforded the target compound. LC-MS (conditions A): tR=0.81 min.; [M+H]+: 392.03 g/mol.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US09242970B2
출처 데이터셋uspto-grants-2016_01
ORD IDord-331404e623804b91b117ade92e542c38
출처 메모uspto-grants-2016_01