Hydrochloric Acid → HCID 68065988, 화합물

HRID 594947노트

반응식

HRID 594947 반응식
C(O)C.[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][N:19](C(OC(C)(C)C)=O)[CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12.Cl>O1CCOCC1>[N:4]1[CH:5]=[CH:6][N:7]2[CH:12]=[C:11]([C:13]3[C:17]4[CH2:18][NH:19][CH2:20][CH2:21][C:16]=4[NH:15][N:14]=3)[CH:10]=[CH:9][C:8]=12

참가 물질

5

반응물 3

HCID 313Hydrochloric AcidHCID 702Ethanol2회HCID 68065989HCID 68065989, 화합물

생성물 1

HCID 68065988HCID 68065988, 화합물

시약·촉매·용매 1

HCID 312751,4-Dioxane용매

실험 절차

In a flask, ethanol (1 mL) was added to tert-butyl 3-(imidazo[1,2-a]pyridin-6-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxylate (0.750 g, 0.0022 mol). Hydrochloric acid in dioxane (4 M, 8 mL) was added to the reaction and was stirred for 30 minutes. Ethanol (5 mL) was added to the reaction, and the resulting solution was concentrated in vacuo. The crude product was progressed to the next step without further purification.

후처리

  1. concentrationthe resulting solution was concentrated in vacuo
  2. customThe crude product was progressed to the next step without further purification

출처 및 근거

ORD 기록
ord-e429da4b082344478720ab47bfa103fd
출처 데이터셋
uspto-grants-2016_01
특허 번호
US09242981B2

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