[C:1]([C:3]1([CH2:19][CH2:20]Br)[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[CH2:8][CH2:7][CH2:6][C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]1=2)#[N:2].[ClH:22].[CH:23]12[CH2:30][CH2:29][CH:26]([CH2:27][CH2:28]1)[CH2:25][NH:24]2.C(=O)([O-])[O-].[K+].[K+].CS(C)=O>C(OCC)C.C(Cl)Cl.C(O)(C)C.O>[ClH:22].[C:1]([C:3]1([CH2:19][CH2:20][N:24]2[CH2:25][CH:26]3[CH2:29][CH2:30][CH:23]2[CH2:28][CH2:27]3)[C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[CH2:8][CH2:7][CH2:6][C:5]2[CH:15]=[CH:16][CH:17]=[CH:18][C:4]1=2)#[N:2]3.1 Parts 12-cyano-12-(2-bromoethyl)-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene, 1.8 parts 2-azabicyclo[2.2.2]octane hydrochloride, 1.8 parts potassium carbonate, 44 parts dimethylsulfoxide and 10 parts water are combined, heated at 100° C. for about 4 hours, and then poured into an ice-water mixture. The resulting gummy precipitate is dissolved in a mixture of ethyl ether and methylene chloride. The organic phase is separated, washed three times with water, dried with sodium sulfate, filtered, and the solvents removed to leave an oil. This oil is dissolved with a solution of HC1 in isopropanol, and precipitated with ethyl ether to give 12-cyano12-[2-(2-azabicyclo[2.2.2]oct-2-yl)ethyl]-5,6,7,12-tetrahydrodibenzo[a,d]cyclooctene hydrochloride. This compound is represented by the following structural formula. ##STR17##
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