Methyl 4-Formylbenzoate → tert-Butyl 4-((4-chlorophenethyl)(4-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylate

HRID 59795

반응식

HRID 59795 반응식
[C:1]([N:8]1[CH2:13][CH2:12][C:11](=O)[CH2:10][CH2:9]1)([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2].[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][NH2:24])=[CH:18][CH:17]=1.[CH:25]([C:27]1[CH:36]=[CH:35][C:30]([C:31]([O:33][CH3:34])=[O:32])=[CH:29][CH:28]=1)=O>>[Cl:15][C:16]1[CH:21]=[CH:20][C:19]([CH2:22][CH2:23][N:24]([CH2:25][C:27]2[CH:28]=[CH:29][C:30]([C:31]([O:33][CH3:34])=[O:32])=[CH:35][CH:36]=2)[CH:11]2[CH2:12][CH2:13][N:8]([C:1]([O:3][C:4]([CH3:7])([CH3:6])[CH3:5])=[O:2])[CH2:9][CH2:10]2)=[CH:18][CH:17]=1

참가 물질

4

반응물 3

HCID 15294Methyl 4-FormylbenzoateHCID 674302-(4-Chlorophenyl)ethylamineHCID 735900tert-Butyl 4-oxopiperidine-1-carboxylate

생성물 1

HCID 121422786tert-Butyl 4-((4-chlorophenethyl)(4-(methoxycarbonyl)benzyl)amino)piperidine-1-carboxylate

실험 절차

The title compound was prepared according to Procedure 1B starting from N-Boc-piperid-4-one, 2-(4-chlorophenyl)ethylamine, and methyl 4-formylbenzoate.

출처 및 근거

ORD 기록
ord-160d257143854337814bdb442468d826
출처 데이터셋
uspto-grants-2016_09
특허 번호
US09440953B2

연결된 노트

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