반응식
[Al](I)(I)I.[CH2:5]([C:8]1[CH:9]=[C:10]([O:16]C)[CH:11]=[C:12]([O:14]C)[CH:13]=1)[CH:6]=[CH2:7]>C(=S)=S>[CH2:5]([C:8]1[CH:13]=[C:12]([OH:14])[CH:11]=[C:10]([CH:9]=1)[OH:16])[CH:6]=[CH2:7]참가 물질
실험 절차
The Pd-catalyzed cross-coupling reaction of 5-Bromo-1,3-dimethoxybenzene with allyl boronic acid pinacol ester produced 5-allyl-1,3-dimethoxybenzene 1 in excellent yield. AlI3 will be used for demethylating 5-Allyl-1,3-dimethoxybenzene with CS2 as solvent to produce 5-allylresorcinol 2. The bis(phosphinite) PCP ligands 3 will be obtained by diphosphorylation of 5-allylresorcinol 2 with the respective chlorophosphine and sodium hydride as a base. Iridium complexes 4 will be obtained from reaction of the respective PCP ligands 3 with [Ir(COD)Cl]2 or [Ir(COE)2Cl]2. Hydrosilylation of complexes 4 will produce the hydrosilylated complexes 5. Reaction of complexes 5 with silica gel will afford the Si2O-supported Ir complexes 6. To date, 5-allyl-1,3-dimethoxybenzene 1 has been prepared in 92% yield.
출처 및 근거
- ORD 기록
- ord-c2d1826b42a845f696bf59f6d9185409
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07902417B2
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