Hydrochloric Acid → 2-(4-Ethylbenzyl)phenol
반응식
C([O:8][C:9]1[CH:14]=[CH:13][CH:12]=[CH:11][C:10]=1[CH:15]([C:17]1[CH:22]=[CH:21][C:20]([CH2:23][CH3:24])=[CH:19][CH:18]=1)O)C1C=CC=CC=1.Cl>[Pd].CO>[CH2:23]([C:20]1[CH:21]=[CH:22][C:17]([CH2:15][C:10]2[CH:11]=[CH:12][CH:13]=[CH:14][C:9]=2[OH:8])=[CH:18][CH:19]=1)[CH3:24]참가 물질
5
실험 절차
Then a mixture of (2-benzyloxyphenyl)(4-ethylphenyl)methanol (78.5 g), 10% palladium activated carbon (5.2 g), concentrated hydrochloric acid (10.4 mL) and methanol (850 mL) was stirred under hydrogen atmosphere at room temperature for 24 hours. After filtering off the insolubles, the filtrate was evaporated under reduced pressure and then, the residue was distilled under reduced pressure to obtain the title compound (56.8 g) as a colorless oil.
후처리
- filtrationAfter filtering off the insolubles
- customthe filtrate was evaporated under reduced pressure
- distillationthe residue was distilled under reduced pressure
출처 및 근거
- ORD 기록
- ord-77976d2026134d0c9284558764173587
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07910619B2
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