Sodium Hydroxide → HCID 178493213, 화합물

HRID 606707노트

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HRID 606707 반응식
[CH3:1][O:2][C:3]1[CH:4]=[CH:5][N:6]=[C:7]([CH2:11][S+:12]([O-:26])[C:13]2[NH:14][C:15]3[CH:16]=[CH:17][C:18]([O:22][CH:23]([F:25])[F:24])=[CH:19][C:20]=3[N:21]=2)[C:8]=1[O:9][CH3:10].[OH-].[Na+:28]>C1(C)C=CC=CC=1>[CH3:1][O:2][C:3]1[CH:4]=[CH:5][N:6]=[C:7]([CH2:11][S+:12]([O-:26])[C:13]2[N-:14][C:15]3[CH:16]=[CH:17][C:18]([O:22][CH:23]([F:24])[F:25])=[CH:19][C:20]=3[N:21]=2)[C:8]=1[O:9][CH3:10].[Na+:28]

참가 물질

4

반응물 2

HCID 14798Sodium HydroxideHCID 178493214Pantoprazole

생성물 1

HCID 178493213HCID 178493213, 화합물

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

A 100 ml flask was charged with toluene (50.0 ml). Pantoprazole (5.0 g, 12.8 mmol) and 47% aqueous NaOH (1.2 g) were added to the stirred solvent at room temperature. The mixture was stirred until dissolution and then overnight until precipitation. The solid was filtered giving pantoprazole sodium. The sample was dried at 45° C. under 10 mm Hg vacuum overnight, giving 4.21 g of amorphous pantoprazole sodium.

후처리

  1. customovernight until precipitation
  2. filtrationThe solid was filtered

출처 및 근거

ORD 기록
ord-24d28905f6e740c4a9e934f355ac8919
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07915423B2

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