Hydrochloric Acid → 3-Methyl-5-phenylethynylpyridine hydrochloride
반응식
[ClH:1].[CH3:2][C:3]1[CH:4]=[N:5][CH:6]=[C:7]([C:9]#[C:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:8]=1>O1CCOCC1.C(OCC)C>[ClH:1].[CH3:2][C:3]1[CH:4]=[N:5][CH:6]=[C:7]([C:9]#[C:10][C:11]2[CH:16]=[CH:15][CH:14]=[CH:13][CH:12]=2)[CH:8]=1참가 물질
5
실험 절차
Add a 4 N solution of hydrogen chloride in 1,4-dioxane (0.6 mL) to a solution of 3-methyl-5-phenylethynylpyridine (0.398 g, 2.06 mmol), (prepared essentially as described in EXAMPLE 1), in diethyl ether (2 mL). Concentrate the reaction mixture and triturate the resulting solid with hexanes and diethyl ether to give the title compound as a solid (0.477 mg, 100%).
후처리
- custom(prepared essentially
- concentrationConcentrate the reaction mixture
- customtriturate the resulting solid with hexanes and diethyl ether
출처 및 근거
- ORD 기록
- ord-5ce516976ecf47aeacdc404f9ef9b176
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07915424B2
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