Hydrochloric Acid → 3-Bromo-5-(4-fluorophenylethynyl)-pyridine hydrochloride
반응식
[ClH:1].[Br:2][C:3]1[CH:4]=[N:5][CH:6]=[C:7]([C:9]#[C:10][C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[CH:8]=1>C(OCC)C>[ClH:1].[Br:2][C:3]1[CH:4]=[N:5][CH:6]=[C:7]([C:9]#[C:10][C:11]2[CH:16]=[CH:15][C:14]([F:17])=[CH:13][CH:12]=2)[CH:8]=1참가 물질
4
실험 절차
Add 1 M hydrogen chloride in diethyl ether (1.1 eq) to 3-bromo-5-(4-fluorophenylethynyl)-pyridine, from PREPARATION 24, in diethyl ether and stir for 2 h. Filter and dry the collected solid under high vacuum to give the title compound.
후처리
- customfrom PREPARATION 24
- filtrationFilter
- customdry the collected solid under high vacuum
출처 및 근거
- ORD 기록
- ord-1a0de6886ecf4be6a0bcda3e56eff07e
- 출처 데이터셋
- uspto-grants-2011_03
- 특허 번호
- US07915424B2
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