Dimethylformamide dimethyl acetal → N'-(5-Cyano-2-methylsulfanyl-thiazol-4-yl)-N,N-dimethyl-formamidine

HRID 607266노트

반응식

HRID 607266 반응식
[NH2:1][C:2]1[N:3]=[C:4]([S:9][CH3:10])[S:5][C:6]=1[C:7]#[N:8].CO[CH:13](OC)[N:14]([CH3:16])[CH3:15]>>[C:7]([C:6]1[S:5][C:4]([S:9][CH3:10])=[N:3][C:2]=1[N:1]=[CH:13][N:14]([CH3:16])[CH3:15])#[N:8]

참가 물질

3

반응물 2

HCID 78373Dimethylformamide dimethyl acetalHCID 6764114-Amino-2-(methylsulfanyl)-1,3-thiazole-5-carbonitrile

생성물 1

HCID 66808347N'-(5-Cyano-2-methylsulfanyl-thiazol-4-yl)-N,N-dimethyl-formamidine수율 99%

실험 절차

The title compound was prepared from the reaction of 4-Amino-2-methylsulfanyl-thiazole-5-carbonitrile with N,N-dimethylformamide dimethyl acetal using the procedure from Example 156B to provide the title compound as a white foam (0.132, g, 99%).

출처 및 근거

ORD 기록
ord-35616c8ed40a48f096aa5ea08bbe0e23
출처 데이터셋
uspto-grants-2011_03
특허 번호
US07915411B2

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